- Shire has appointed Andreas Busch as executive vice president, head of research and development and chief scientific officer.

He will replace Howard Mayer, who will become Shire's chief medical officer.

Busch is currently head of drug discovery at Bayer, where he had worked for 13 years, Shire said.

"Andy is an outstanding scientist with extensive experience leading research and development functions, and an established track record of building broad portfolios that encompass both biologics and small molecules," Shire chief executive Flemming Ornskov said.

"We look forward to Andy enabling us to further accelerate our ability to discover novel treatments for our innovative rare disease pipeline."

At 8:34am: [LON:SHP] Shire PLC share price was +35p at 3696.5p

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